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杨铁虹副教授科研成果
2010-04-15 17:46   发布范围:公开

 

 

 

 

 

    在中药多糖的制备、结构修饰、抗肿瘤、抗艾滋病及免疫药理等方面作了较深入的工作,并参与了新药的临床前毒理学研究。负责或参加了多项国家863、国家自然科学基金、军队、省级和校级课题的研究。共发表科研论文30余篇,作为主要完成人获得陕西省科技进步一等奖1项,获得国家发明专利1项。

代表论文:

1.Tiehong Yang,Min Jia,Jia Meng,Hong Wu,Qibing Mei.Immunomodulatory activity of polysaccharide isolated from Angelica sinensis.Int J Biol Macromol,2006,39:179-184

2.Peng Shang,Ai-Rong Qian,Tie-Hong Yang,Min Jia,Qi-Bing Mei,Chi-Hin Cho,Wen-Ming Zhao,Zhi-Nan Chen.Anti-tumor effects of polysaccharides from Angelica. World J Gastroenterol.2003,9(9):1963-1967

3.Wei Cao,Xiao-Qiang Li,Li Liu,Tie-Hong Yang,Chen Li,Qi-Bing Mei.Structure of an anti-        tumor polysaccharide from Angelica sinensis (Oliv.) Diels.Carbohydrate polymers, 2006,64:149-159

4.Zhu B,Wu Y,Shen C,Yang T,Deng Y,Xun X,Tian Y,Yan J,Li T.Genetic analysis of 17 Y-chromosomal STRs haplotypes of Chinese Tibetan ethnic group residing in Qinghai province of China.Forensic Sci Int.in press

5.Hongping Zhao,Buling Wu,Hong Wu,Lingyun Su,Jianliang Pang,Yanli Liu,Tiehong Yang. Intranasal immunization with Streptococcus mutans glucan-binding protein D encapsulated into chitosan coated PLGA microspheres induces protective immunity in rats. Biotechnology Letters,2006(28)1299 -1304

6.Li Fan,Hong Wu,Hui Zhang,Fei Li,Tie-hong Yang,Chun-hu Gu.Super pH-sensitive anticarcinogen carrier for tumor specific delivery: an in vitro study.Carbohyd Polym (in press)

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